There are plenty international airlines flying to Ghana, especially from Europe and they all land in Kotoka International airport at Accra.
A normal flight from London may take 6 hours and 30 minutes and from New York around 10 hours.
Avoid flying to Ghana only with a one-way ticket because you may find some problems with airport immigration officials if you don’t have a return ticket.
Also, when you decide to return home, you'll find that flights out of Accra are very expensive, so you’ll almost certainly end up paying twice as much for a cheap return.
Check out some of the airlines flying to Ghana: